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The Biology of Exercise

WebSean L. McGee and Ken R. Walder. Omics and Exercise: Global Approaches for Mapping Exercise Biological Networks. Nolan J. Hoffman. Regular exercise is among the most …

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Hemoglobin and Its Diseases

WebThe inherited disorders of hemoglobin are by far the commonest Mendelian diseases. It is estimated that between 300,000 and 400,000 babies are born with these conditions each …

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Health Benefits of Exercise

WebThe aim of this introduction is briefly to document facts that health benefits of physical activity predate its readers. In the 5th century BC, the ancient physician …

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Health Benefits of Exercise

WebOverwhelming evidence exists that lifelong exercise is associated with a longer health span, delaying the onset of 40 chronic conditions/diseases. What is …

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Iron Deficiency Anemia: A Common and Curable Disease

WebIron deficiency anemia arises when the balance of iron intake, iron stores, and the body's loss of iron are insufficient to fully support production of erythrocytes. Iron …

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The Skin and Its Diseases

WebThe Italian philologist and physician Geronimo Mercuriali published the first textbook on the skin and its diseases in 1572. Today, however, we are at a nexus in modern biology …

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Health Benefits of Exercise

WebOverwhelming evidence exists that lifelong exercise is associated with a longer health span, delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is …

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Skeletal Muscle as an Endocrine Organ: The Role of Myokines in …

WebMoreover, transgenic expression of transcriptional key regulator peroxisome proliferator-activated receptor coactivator (PGC)1α in skeletal muscle led to the discovery of irisin …

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Roles of NAD+ in Health and Aging

WebThe Four Classes of NAD +-Consuming Proteins . NAD + is a cosubstrate for at least four main classes of enzymes producing NAM as a byproduct of their consumption of NAD …

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Iron Deficiency Anemia: A Common and Curable Disease

WebIron deficiency anemia arises when the balance of iron intake, iron stores, and the body's loss of iron are insufficient to fully support production of erythrocytes. Iron deficiency …

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World Distribution, Population Genetics, and Health Burden of the

WebThe inherited disorders of hemoglobin are by far the most common monogenic diseases. Recent surveys suggest that between 300,000 and 400,000 babies are born with a …

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From Life Span to Health Span: Declaring “Victory” in the Pursuit of

WebON THE ORIGIN OF LIFE SPAN. How long people live as individuals, the expected duration of life of people of any age based on current death rates in a national population, and the …

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Cold Spring Harbor Perspectives in Medicine

WebFollow us on Twitter; Cold Spring Harbor Perspectives in Medicine — a new online publication covering everything from the molecular and cellular bases of disease …

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Hemoglobin Variants: Biochemical Properties and Clinical Correlates

WebFigure 1. The structure of Hb. (A) The α (pink) and β (red) Hb subunits have conserved α-helical folds.Helices are labeled A–H from the amino terminus. The α subunit lacks helix …

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Roles of NAD+ in Health and Aging

WebNAD +, the essential metabolite involved in multiple reactions such as the regulation of cellular metabolism, energy production, DNA repair, mitophagy and …

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Why Is Organ Transplantation Clinically Important

WebThe clinical importance of solid organ transplantations may be evaluated according to their impact on patient survival, the reduction of comorbidity, improvement of labor life, and …

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Health Benefits of Exercise

WebMolecular Cloning The New Edition Buy Now and Save 30% Paperback only (limited time offer)

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Roles of NAD in Health and Aging

WebNAD+ is an essential metabolite for life and health, as it participates in dozens of known cellular reactions that affect redox status, energy production, and metabolic homeostasis, …

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Bone Remodeling and the Microbiome

WebThere is now strong evidence that the gut microbiome regulates bone homeostasis in health and disease, and that prebiotic and probiotics protect against bone loss. Herein, the …

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