Mcdb.ucsb.edu

Biomedical Sciences MCDB UC Santa Barbara

WEBBiomedical research in MCDB spans a wide variety of areas and medical fields from basic research all the way to pre-clinical experimentation and direct medical application. MCDB researchers investigate molecular disease mechanisms, diagnostic approaches and biomarkers, pharmacological interventions and novel drug design, therapies including

Actived: 4 days ago

URL: https://www.mcdb.ucsb.edu/research/biomedical-sciences

New test reveals existing antibiotics, hiding in plain sight …

WEBA new antibiotic susceptibility test revealed that existing FDA-approved antibiotics can effectively treat multidrug-resistant infections.

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Microbiology & Immunology MCDB UC Santa Barbara

WEBMicrobiology and immunology research and training in the MCDB Department focuses on the study of mechanisms of regulation of gene expression and function in microorganisms including bacteria and ciliates, cultured animal cells, and animal models of infectious disease. Host interactions with microbial and viral pathogens, the molecular bases of

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How do cells sense, respond, and adapt to protein-folding stress …

WEBCells rely on complex cellular stress response networks to preserve homeostasis. Detecting and appropriately responding to internal imbalances allows the cell to maintain a healthy proteome and an intact genome. How do cells maintain the health of their transcriptome? How to different stress signaling pathways integrate to allow a cell to make decisions?

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Network re-wiring in disease Diego Acosta-Alvear Lab

WEBAll cellular stress responses control the survival/death decision. Therefore, these homeostatic networks are often re-wired in disease, allowing abnormal cells to evade apoptosis and thrive. How does network re-wiring turn these finely tuned homeostats into maladaptive cytoprotectors?

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UCSB News Release: "KetoCitra is Here: A long-awaited medical …

WEBKetoCitra is Here A long-awaited medical food developed for patients with Polycystic Kidney Disease (PKD) is now available By Sonia Fernandez Monday, November 29, 2021 - 16:30, Santa Barbara, CA Two years in the making, a medical food conceived and developed by UC Santa Barbara molecular biologists specifically for people with polycystic kidney …

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Diego Acosta-Alvear Diego Acosta-Alvear Lab

WEBOur lab investigates the molecular mechanisms by which cellular stress response networks reinstate homeostasis or promote cell death. By understanding how these networks are wired in healthy cells we can discern how they become re-wired during disease.

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When bad cells go good: harnessing cellular cannibalism for …

WEBHarnessing haywire cells. The implications of these insights expanded in January 2020, when co-author Meghan Morrissey interviewed for a faculty position at UCSB. In her talk she described programming macrophages to eat cancer cells as a novel treatment for the disease, an approach called CAR-M. Morrissey had found that adding …

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Researchers examine the role of low-carb/low-sugar diets in …

WEBFighting PKD at the Dinner Table: Researchers examine the role of low-carb/low-sugar diets in warding off polycystic kidney disease. The team of UC Santa Barbara biochemist Thomas Weimbs published the results of a clinical study that gives the first indication that ketogenic diets may be safe and effective in patients with polycystic kidney disease (PKD).

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Supporting Kidney Disease Research MCDB UC Santa …

WEBSupporting Kidney Disease Research. The Weimbs Lab welcomed a special guest to campus. By Sonia Fernandez. UC Santa Barbara molecular biologist Thomas Weimbs, left, recently welcomed Glenn Frommer, right, to the campus as the latter whizzed through Santa Barbara on a 5,300 mile Ride for PKD. The Weimbs Lab was one of the …

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Thomas Weimbs, PhD Thomas Weimbs Lab UC Santa …

WEBThe Weimbs laboratory studies molecular mechanisms underlying polycystic kidney disease (PKD) with an emphasis on developing new therapies. Research from Dr. Weimbs’ lab has led to a better understanding of PKD and led to novel methods to deliver therapeutics specifically to polycystic kidneys. Some of the most recent research has led to the …

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Alumni Denise Montell Lab Molecular, Cellular, and …

WEBMariana Melani. Position After Graduation: Postdoctoral fellow, National Institutes of Health. Current Position: Associate Investigator, National Council of Research and Technology, Leloir Institute, Argentina. Years in Lab: 2004-2008.

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Zen and the art of mitochondrial maintenance: The …

WEBWhile we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or “healthspan,” that precedes the inevitable decline of advancing age. Researchers at UC Santa Barbara have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life …

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Huishi Toh Dennis O. Clegg Lab UC Santa Barbara

WEBI work on understanding the initial transition into diet-induced diabetes using the Nile rat (Arvicanthis Niloticus) model. Type 2 diabetes is a multifactorial disease mainly driven by nutritional stresses and the extent of its broad ranging health problems is heavily biased by genetics. We chose the Nile rat model, recently in the Genome Spotlight of TheScientist …

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Supporting Kidney Disease Research: The Weimbs Lab welcomed …

WEBBy Sonia Fernandez Tuesday, May 17, 2022 - 14:45 Santa Barbara, CA UC Santa Barbara molecular biologist Thomas Weimbs, left, recently welcomed Glenn Frommer, right, to the campus as the latter whizzed through Santa Barbara on a 5,300 mile Ride for PKD. The Weimbs Lab was one of the stops on this ambitious bicycle odyssey to raise awareness …

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Student Financial Support MCDB UC Santa Barbara

WEBStudent Financial Support. The Molecular, Cellular and Developmental Biology Graduate Program is committed to fully funding PhD students during their academic career in MCDB. PhD financial support will come in the form of Graduate Student Research positions, Teaching Assistantships (TA), and fellowships. The current stipend is $36,000 annually.

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Ketogenic metabolic therapy for chronic kidney disease – the …

WEBKetogenic metabolic therapy for CKD 3 Figure Long-term,1: persistent duetohyperglycemia (SAD the instandard sugar,American diet ) high carbohydrates, calories and highly processed foods leads to chronic hyperinsulinemia,insulin-resistance,hypertension,chronic inflammation,and renal tissue damage.In the presence of insulin,excess carbohydrates are

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Ketogenic metabolic therapy for chronic kidney disease – the …

WEB2 T.Weimbs et al. circulating fatty acids and ketones then become the main energy supply for most cells and tissues instead of blood glucose. Ketosis induced by fasting is a form of KMT.

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