Jneuroinflammation.biomedcentral.com

Microglia in depression: an overview of microglia in the …

WebMajor depressive disorder (MDD) is a public health problem that affects approximately 322 million people worldwide [].During the coronavirus disease 2019 …

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URL: https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-022-02492-0

Impact of microbiota on central nervous system and neurological

WebAbundant and diverse microbial communities coexist in humans and mice. Majority of these microorganisms including bacteria, archaea, fungi, and viruses reside in …

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The function of gut microbiota in immune-related neurological …

WebThe GI tract is a highly complex organ composed of microorganisms, the intestinal epithelium, and the mucosal immune system. The microorganisms living in the …

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Inflammation: the link between comorbidities, genetics, and …

WebAlzheimer’s disease (AD) is a neurodegenerative disorder, most cases of which lack a clear causative event. This has made the disease difficult to characterize …

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The progress of gut microbiome research related to brain disorders

WebBBB is a semipermeable barrier composed of specialized endothelial cells in the microvasculature [].The BBB separates the CNS from the peripheral blood [].There …

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Chronic stress-induced depression requires the recruitment of

WebDepression is a recurrent and devastating mental disease that is highly prevalent worldwide. Prolonged exposure to stressful events or a stressful environment …

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Mitochondrial dysfunction in microglia: a novel perspective for

WebAlzheimer's disease (AD) is the most common neurodegenerative disease in the elderly globally. Emerging evidence has demonstrated microglia-driven …

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Inflammatory and cytotoxic effects of bifenthrin in primary …

WebPyrethroids, such as bifenthrin (BF), are among the most widely used class of insecticides that pose serious risks to human and wildlife health. Pyrethroids are …

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Interleukin-9 protects from microglia- and TNF-mediated …

WebBackground Multiple sclerosis (MS) is a progressive neurodegenerative disease of the central nervous system characterized by inflammation-driven synaptic …

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Dysregulated brain-gut axis in the setting of traumatic brain injury

WebTraumatic brain injury (TBI) is a chronic and debilitating disease, associated with a high risk of psychiatric and neurodegenerative diseases. Despite significant …

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Neural networks and the anti-inflammatory effect of …

WebTranscutaneous auricular vagus nerve stimulation (taVNS) is a relatively non-invasive alternative treatment for patients suffering from major depressive disorder …

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Neuroinflammation and psychiatric illness Journal of

WebMultiple lines of evidence support the pathogenic role of neuroinflammation in psychiatric illness. While systemic autoimmune diseases are well-documented causes of …

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Fractalkine isoforms differentially regulate microglia-mediated

WebDiabetic retinopathy (DR) affects about 200 million people worldwide, causing leakage of blood components into retinal tissues, leading to activation of microglia, the …

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Cyanidin-3-O-glucoside protects the brain and improves cognitive

WebCyanidin-3-O-glucoside (C3G) is a natural anthocyanin with antioxidant, anti-inflammatory, and antitumor properties. However, as the effects of C3G on the …

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NAD+ improves cognitive function and reduces …

WebNAD + treatment mitigated impairment of learning and memory in CCH rats. The BCCAO model is a classic animal model that mimics CCH. After the BCCAO …

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Central intracrine DHEA synthesis in ageing-related …

WebIt is a well-known fact that DHEA declines on ageing and that it is linked to ageing-related neurodegeneration, which is characterised by gradual cognitive decline. …

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Global, regional, and national burden of Guillain–Barré syndrome …

WebOverview. This study is part of the GBD 2019 project, which was conducted by the Institute for Health Metrics and Evaluation (IHME) to provide a systematic …

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Peripheral blood amyloid-β involved in the pathogenesis of …

WebAlzheimer’s disease (AD) is the most common age-associated dementia with progressive loss of memory and cognitive functions [].It is predicted that by 2050, …

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Gut microbiota, circulating cytokines and dementia: a Mendelian

WebSome studies have shown that gut microbiota may be associated with dementia. However, the causal effects between gut microbiota and different types of …

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Integration of National Health Insurance claims data and animal …

WebBackground Parkinson’s disease (PD) is a common and costly progressive neurodegenerative disease of unclear etiology. A disease-modifying approach that can …

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