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Burden of anemia and its underlying causes in 204 countries and

In 2019, the national age-standardized point prevalence of anemia ranged from 3118.0 to 49,327.1 cases per 100,000 population. Zambia [49327.1 (95% UI: 46,838.5–51,700.1)], … See more

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URL: https://jhoonline.biomedcentral.com/articles/10.1186/s13045-021-01202-2

The global, regional, and national burden of cancer among …

WEBCancer, as a major disease cluster of noncommunicable diseases, is a global health problem affecting populations of all ages [].Despite global commitment to …

Category: Cancer Go Health

Global, regional, and national cancer incidence and death for 29 …

WEBAccording to the World Health Organization (WHO) statistics, in 2019, cancer ranks as the first or second leading cause of death in 112 countries globally and …

Category: Cancer Go Health

Role of lysosomes in physiological activities, diseases, and therapy

WEBLong known as digestive organelles, lysosomes have now emerged as multifaceted centers responsible for degradation, nutrient sensing, and immunity. …

Category: Health Go Health

Journal of Hematology & Oncology Full Text

WEBInvestigations of disease incidence, mortality, and disability-adjusted life years (DALYs) are valuable for facilitating preventive measures and health resource …

Category: Health Go Health

Proteomic signatures of 16 major types of human cancer reveal …

WEBProteomic characterization of cancers is essential for a comprehensive understanding of key molecular aberrations. However, proteomic profiling of a large …

Category: Cancer Go Health

Incidence and death in 29 cancer groups in 2017 and trend …

WEBCancer has become the second most serious disease threatening human health, followed by cardiovascular diseases. This study aimed to quantitatively estimate …

Category: Cancer Go Health

Role of CD47 in Hematological Malignancies Journal of …

WEBCD47, or integrin-associated protein, is a cell surface ligand expressed in low levels by nearly all cells of the body. It plays an integral role in various immune …

Category: Health Go Health

Global burden of breast cancer and attributable risk factors in 195

WEBBackground Statistical data on the incidence, mortality, and burden of breast cancer and the relevant risk factors are valuable for policy-making. We aimed to …

Category: Cancer Go Health

Advances in the diagnosis and treatment of sickle cell disease

WEBSickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and more than 3 million worldwide, is caused by mutations in the βb globin …

Category: Health Go Health

Recent advances in therapeutic strategies for triple-negative …

WEBTriple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer (BC) with a poor prognosis. Current treatment options are limited to …

Category: Cancer Go Health

Recent advances in targeted therapies in acute myeloid leukemia

WEBAcute myeloid leukemia (AML) is the most common acute leukemia in adults. AML is thought to arise from somatically acquired mutations, which is a fairly …

Category: Health Go Health

RNA sequencing: new technologies and applications in cancer …

WEBOver the past few decades, RNA sequencing has significantly progressed, becoming a paramount approach for transcriptome profiling. The revolution from bulk …

Category: Health Go Health

1-year survival in haemophagocytic lymphohistiocytosis: a …

WEBHaemophagocytic lymphohistiocytosis (HLH) is a lethal syndrome of excessive immune activation. We undertook a nationwide study in England of all cases …

Category: Health Go Health

NK cell-based cancer immunotherapy: from basic biology to …

WEBNK cell biology. NK cells were identified over four decades ago as lymphocytes with innate ability to lyse tumor cells without the need for prior sensitization …

Category: Health Go Health

Gut microbiota influence immunotherapy responses: mechanisms …

WEBThe gut microbiota have long been recognized to play a key role in human health and disease. Currently, several lines of evidence from preclinical to clinical …

Category: Health Go Health

Nanomaterials for cancer therapy: current progress and …

WEBCancer is a disease with complex pathological process. Current chemotherapy faces problems such as lack of specificity, cytotoxicity, induction of multi …

Category: Cancer Go Health

Ayurvedic herbal medicine and lead poisoning Journal of …

WEBAyurvedic medicine is a traditional system native to India [ 1 ]. This system stresses the use of natural plant-based medicines, and minerals including sulfur, …

Category: Medicine Go Health

Advances of medical nanorobots for future cancer treatments

WEBUsing nanomolecular scale tools and biological nanomolecular knowledge of the human body, nanomedicines were designed to aim at treating and preventing …

Category: Medicine Go Health