Iris.epa.gov

IRIS Toxicological Review of Trimethylbenzenes (Final Report)

WEBEPA has finalized the Integrated Risk Information System (IRIS) Assessment of Trimethylbenzenes (TMBs).This assessment addresses the potential non-cancer and cancer human health effects from long-term exposure to TMBs. Now final, this assessment will be the first IRIS assessment for TMBs that may be used by EPA’s program and …

Actived: 6 days ago

URL: https://iris.epa.gov/Document/&deid=246041

Health Assessment Of 1,3-Butadiene IRIS US EPA

WEBThis assessment was conducted to review the new information that has become available since EPA's 1985 health assessment of 1,3-butadiene. 1,3-Butadiene is a gas used commercially in the production of styrene-butadiene rubber, plastics, and thermoplastic resins. The major environmental source of 1,3-butadiene is the incomplete …

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IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and …

WEBEPA has finalized the IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts This assessment addresses the potential cancer and noncancer human health effects from exposure to perfluorobutanoic acid and related salts. EPA’s program and regional offices may use this assessment to inform decisions to protect human health

Category:  Cancer Go Health

Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide …

WEBDec 2016. EPA posted the final Evaluation of the Inhalation Carcinogenicity of Ethylene Oxide to the IRIS database. 24-. Oct 2016. EPA submitted a revised draft for final Agency Review and Interagency Science Discussion. 23-. Aug 2015. EPA's SAB issued a final report on its review of the draft assessment of EtO. 21-.

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What is the Integrated Risk Information System (IRIS)

WEBThis IRIS assessment addresses the potential cancer and noncancer human health effects from inhalation exposure to Libby Amphibole asbestos (LAA). The noncancer findings of this assessment concluded that exposure to LAA may cause thickening of the pleura. The pleura are the membranes that envelop the lungs and line the chest cavity.

Category:  Cancer Go Health

IRIS Toxicological Review of Benzo[A]Pyrene (Final Report) IRIS

WEBEPA has finalized the Integrated Risk Information System (IRIS) assessment of benzo [a]pyrene. This assessment addresses the potential cancer and noncancer human health effects from long-term exposure to benzo [a]pyrene. Now final, this assessment will update the toxicological information on benzo [a]pyrene posted in 1987.

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Supplementary Guidance for Conducting Health Risk Assessment …

WEBThis document is a supplement to the EPA Guidelines for the Health Risk Assessment of Chemical Mixtures of 1986. The 1986 Guidelines represent the Agency's science policy and are a procedural guide for evaluating data on the health risks from exposures to chemical mixtures. The emphasis is on dose response and risk …

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Toxicological Review of Ammonia (Noncancer Inhalation)

WEBEPA/635/R-16/163Fa www.epa.gov/iris . Toxicological Review of Ammonia Noncancer Inhalation [CASRN 7664-41-7] September. 2016 . Integrated Risk Information System

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IRIS Toxicological Review of Inorganic Arsenic (Public Comment …

WEB[UPDATE] In Dec 2023, EPA released BMD Model Code and BMD Modeling Results provided for the draft IRIS Toxicological Review of Inorganic Arsenic. This was announced in the Federal Register for a 15-day public comment and review period. [Federal Register Notice Dec 29, 2023]

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IRIS Toxicological Review of Chloroprene (Final Report)

WEBThe final Toxicological Review of Chloroprene provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to chloroprene. Chloroprene (C4H5Cl) is a volatile, flammable liquid used primarily in the manufacture of polychloroprene or neoprene rubber. The latter is used to make diverse products, such …

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Chloroform CASRN 67-66-3 IRIS US EPA, ORD

WEBA dose of 1 x 10 -2 mg/kg-day (equal to the RfD) can be considered protective against cancer risk. Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (41 pp, 234 K) Inhalation Unit Risk: 2.3 x 10 -5 per µg/m 3. Extrapolation Method: Linearized multistage procedure, extra risk. Tumor site (s): Hepatic.

Category:  Cancer Go Health

Toxicological Review of Phenol (CAS No. 108-95-2) (PDF)

WEBEPA/635/R-02/006 TOXICOLOGICAL REVIEW OF Phenol (CAS No. 108-95-2) In Support of Summary Information on the Integrated Risk Information System (IRIS)

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Toxicological Review of Ammonia Noncancer Inhalation: …

WEBAmmonia occurs naturally Occurrence and Health Effects. Exposure by Ammonia to ammonia as part of normal biological r. A processes. is also produced. concentrations ammonia in indoor primarily agricultural , drinking breathing or direct air in many cleaning products. 3 containing contact. Measured ammonia.

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Toxicological Review of Benzo[a]pyrene – Executive Summary …

WEBSummary of Occurrence and Health Effects. Benzo[a]pyrene component Benzo[a]pyrene is a polycyclic aromatic cigarettes, of smoke industrial is can occur by coal, as processes, hydrocarbon atmosphere and petroleum products). products, such as charred meats, where benzo[a]pyrene exposure to benzo[a]pyrene is certain food the cooking products

Category:  Food Go Health

Nitrogen dioxide (CASRN 10102-44-0) IRIS US EPA

WEBCASRN — 10102-44-0. The RfD for nitrogen dioxide has been withdrawn from IRIS as of 09/01/1994 based on the fact that nitrogen dioxide does not exist per se in water, since it reacts instantaneously with water to form nitric and nitrous acids (U.S. EPA, 1993). In the presence of alkali (pH > 7.0), nitrates and nitrites are formed

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Nitrate; CASRN 14797-55-8

WEBNitrate; CASRN 14797-55-8. Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the IRIS assessment development process. Sections I (Health Hazard Assessments for Noncarcinogenic Effects) and II (Carcinogenicity Assessment for …

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Perfluorohexanoic Acid (PFHxA) CASRN 307-24-4 IRIS

WEBSystem RfD (mg/kg-day) Basis PoD Composite UF Confidence; Developmental: 5 x 10 -4 (Chronic) Decreased postnatal (PND 0) body weight in F1 Sprague‑Dawley male and female rats

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Zineb; CASRN 12122-67-7

WEBCASRN — 12122-67-7. Last Revised — 03/31/1987. The oral Reference Dose (RfD) is based on the assumption that thresholds exist for certain toxic effects such as cellular necrosis. It is expressed in units of mg/kg-day. In general, the RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the

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Arsenic, inorganic; CASRN 7440-38-2

WEBI.A. Reference Dose for Chronic Oral Exposure (RfD) Substance Name — Arsenic, inorganic. CASRN — 7440-38-2. Last Revised — 09/01/1991. The oral Reference Dose (RfD) is based on the assumption that thresholds exist for certain toxic effects such as cellular necrosis. It is expressed in units of mg/kg-day.

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