Gvt-journal.biomedcentral.com

Is gene therapy a good therapeutic approach for HIV-positive …

Despite thousands of researchers worldwide working on a cure for HIV infection, none of the modalities have been completely successful. Currently, four classes of anti-retroviral drugs are available: nucleoside/nucleotide analogs, non-nucleoside … See more

Actived: 8 days ago

URL: https://gvt-journal.biomedcentral.com/articles/10.1186/1479-0556-5-5

The significance of controlled conditions in lentiviral vector

WEBThe inoculum volume of the vector and the number of target cells affect vector titre determination, but not proportionally. Figure 1 shows that during the lentiviral …

Category: Health Go Health

HCV entry receptors as potential targets for siRNA-based …

WEBHCV infection is a major health problem; more than 350 million people worldwide and 10% of the population in Pakistan are chronically infected with this …

Category: Health Go Health

A brief review on dengue molecular virology, diagnosis, treatment …

WEBDengue virus infection is a serious health problem infecting 2.5 billion people worldwide. Dengue is now endemic in more than 100 countries, including …

Category: Health Go Health

Targeting wild-type Erythrocyte receptors for Plasmodium

WEBBackground Malaria causes immense human morbidity and mortality globally. The plasmodium species vivax and falciparum cause over 75 % clinical malaria …

Category: Health Go Health

Genetic immunization with Hantavirus vaccine combining …

WEBIn this research, we developed a novel chimeric HTNV-IL-2-G2 DNA vaccine plasmid by genetically linking IL-2 gene to the G2 segment DNA and tested whether it …

Category: Health Go Health

Characterization of a potent non-cytotoxic shRNA directed to the …

WEBCCR5 shRNA expressed from U6 promoter are effective but cytotoxic to primary PBMCs. Using published algorithms[] to predict potent shRNA sequences, we …

Category: Health Go Health

The recombinant adeno-associated virus vector (rAAV2)-mediated

WEBBackground In humans, overproduction of apolipoprotein B (apoB) is positively associated with premature coronary artery diseases. To reduce the levels of …

Category: Health Go Health

Electroporation by nucleofector is the best nonviral transfection

WEBIn CoASMC, use of FuGENE 6 achieved the best results. It produced almost twice as much CAT per ml media than cells transfected using the second best …

Category: Health Go Health

In-vitro model systems to study Hepatitis C Virus

WEBHepatitis C virus (HCV) is a major cause of chronic liver diseases including steatosis, cirrhosis and hepatocellular carcinoma. Currently, there is no vaccine …

Category: Health Go Health

DNA vaccine constructs against enterovirus 71 elicit

WEBEnterovirus 71 (EV71) is a major causative viral agent responsible for large outbreaks of hand, foot and mouth disease (HFMD), a common rash illness in children …

Category: Health Go Health

Establishment of stable Huh-7 cell lines expressing various …

WEBHepatitis C virus (HCV) is an enveloped plus-strand RNA virus of family Flaviviridae [1, 2].HCV is a major leading cause of chronic liver disease [].An estimated …

Category: Health Go Health

DNA-vaccination via tattooing induces stronger humoral and …

WEBTattooing is one of a number of DNA delivery methods which results in an efficient expression of an introduced gene in the epidermal and dermal layers of the …

Category: Health Go Health

Genetic Vaccines and Therapy BioMed Central

WEBBioMed Central Page 1 of 13 (page number not for citation purposes) Genetic Vaccines and Therapy Research Open Access DNA vaccine constructs against enterovirus 71 elicit …

Category: Health Go Health

Molecular relationship between field and vaccine strain of measles

WEBCountrywide 5.9 million, 0-11 Month old children are immunized annually by EPI (Expended Program on Immunization) against 8 vaccine preventable diseases …

Category: Health Go Health

In vitro evaluation of a double-stranded self-complementary …

WEBBackground Both adenoviral and lentiviral vectors have been successfully used to induce bone repair by over-expression of human bone morphogenetic protein 2 …

Category: Health Go Health

Genetic Vaccines and Therapy BioMed Central

WEBBioMed Central Page 1 of 9 (page number not for citation purposes) Genetic Vaccines and Therapy Research Open Access Prevention of airway inflammation with topical cream …

Category: Health Go Health

Recombinant adeno-associated virus type 2-mediated gene …

WEBBackground Leber's congenital amaurosis (LCA) is a severe form of retinal dystrophy. Mutations in the RPE65 gene, which is abundantly expressed in retinal …

Category: Health Go Health

Sustained protective rabies neutralizing antibody titers after

WEBVaccination of rabbits with rabies G protein pDNA results in sustained high protective neutralizing titers. Groups of three rabbits were vaccinated with either the …

Category: Health Go Health

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