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Defining the oral microbiome by whole-genome …

Based on the results obtained by WGS, showing that oral rinse samples can be considered more representative, compared to saliva, of the whole oral microbiome, HOM resistome was characterized on oral rinse specimens. … See more

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URL: https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-020-01801-y

Defining the healthy "core microbiome" of oral microbial …

WebBackground Most studies examining the commensal human oral microbiome are focused on disease or are limited in methodology. In order to diagnose and treat diseases at an early and reversible stage an in-depth definition of health is indispensible. The aim of this study therefore was to define the healthy oral microbiome using recent …

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The gut-lung axis in critical illness: microbiome …

WebThe healthy individuals, the microbiota displays impressive stability and distinctiveness among various anatomical regions, encompassing the gut, lungs, nasal cavity, and vagina [1,2,3].The microorganisms residing in the lungs and gut serve vital functions in preserving the host's structural integrity, regulating nutrient metabolism, and …

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The Firmicutes/Bacteroidetes ratio of the human …

WebIn humans, the intestinal microbiota plays an important role in the maintenance of host health by providing energy, nutrients, and immunological protection. Applying current molecular methods is necessary to surmount the limitations of classical culturing techniques in order to obtain an accurate description of the microbiota …

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Aging progression of human gut microbiota

WebBackground Human gut microbiota are important for human health and have been regarded as a “forgotten organ”, whose variation is closely linked with various factors, such as host genetics, diet, pathological conditions and external environment. The diversity of human gut microbiota has been correlated with aging, which was characterized by …

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Biofilms and their role on diseases

WebBiofilms are complex, three-dimensional structures that provide a long-established survival mechanism for microorganisms. Biofilms play a substantial role in pathogenesis as they can evade the immune response and be highly resistant to conventional antimicrobials, thus impacting the human health and healthcare system. To …

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Comparative meta-analysis of antimicrobial resistance …

WebAntimicrobial resistance (AMR) is a critical global issue that poses significant threats to human health, animal welfare, and the environment. With the increasing emergence of resistant microorganisms, the effectiveness of current antimicrobial medicines against common infections is diminishing. This study aims to conduct a competitive meta …

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A review of emerging health threats from zoonotic New …

WebDespite repeated spillover transmission and their potential to cause significant morbidity and mortality in human hosts, the New World mammarenaviruses remain largely understudied. These viruses are endemic to South America, with animal reservoir hosts covering large geographic areas and whose transmission ecology and spillover potential …

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The effects of daily fasting hours on shaping gut …

WebIt has recently been reported that intermittent fasting shapes the gut microbiota to benefit health, but this effect may be influenced to the exact fasting protocols. The purpose of this study was to assess the effects of different daily fasting hours on shaping the gut microbiota in mice. Healthy C57BL/6 J male mice were subjected to 12, …

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Common antibiotics, azithromycin and amoxicillin, affect …

WebThe microbiome of the human gut serves a role in a number of physiological processes, but can be altered through effects of age, diet, and disturbances such as antibiotics. Several studies have demonstrated that commonly used antibiotics can have sustained impacts on the diversity and the composition of the gut microbiome. The …

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Zoonoses and emerging pathogens BMC Microbiology Full Text

WebZoonoses represent a major challenge for many disciplines, including microbiology, epidemiology, veterinary, medicine and ecology. Moreover, they pose severe risks to human health and economy. In this editorial, we invite contributions to a BMC Microbiology collection on ‘Zoonoses and emerging pathogens’, covering research on …

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Meta-analysis of the effects of proton pump inhibitors on the …

WebMounting evidence has linked changes in human gut microbiota to proton pump inhibitor (PPI) use. Accordingly, multiple studies have analyzed the gut microbiomes of PPI users, but PPI–microbe interactions are still understudied. Here, we performed a meta-analysis of four studies with available 16S rRNA gene amplicon sequencing data to …

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Changes of gut microbiota and short chain fatty acids in patients …

WebPeutz–Jeghers Syndromeis a rare autosomal dominant genetic disease characterized by gastrointestinal hamartomatous polyps and skin and mucous membrane pigmentation. The pathogenesis of PJS remains unclear; however, it may be associated with mutations in the STK11 gene, and there is currently no effective treatment available. The …

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Yoghurt consumption is associated with changes in the …

WebYoghurt contains live bacteria that could contribute via modulation of the gut microbiota to its reported beneficial effects such as reduced body weight gain and lower incidence of type 2 diabetes. To date, the association between yoghurt consumption and the composition of the gut microbiota is underexplored. Here we used clinical variables, …

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Sex, health status and habitat alter the community composition …

WebFrogs are critical economic animals essential to agricultural ecosystem equilibrium. However, Meningitis-like Infectious Disease (MID) often affects them in agricultural settings. While frog-associated microbiota contribute to elemental cycling and immunity, the effects of frog sex and health on gut bacteria remain understudied, and …

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High frequency of antimicrobial resistance in Salmonella and

WebDiarrhoea is a public health problem where sub-Saharan Africa and South Asia bear the highest burden of the disease [].It is the leading cause of death worldwide, especially among infants and young children [], with 1.57 million deaths recorded in 2017 in sub-Saharan Africa [1, 3, 4] .Most cases of diarrhoea are associated with either the …

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Insights into estrogen impact in oral health & microbiome in …

WebDemographic, clinical characteristics and oral health status. Sixty subjects were included in the study and were divided into three groups, premenopausal (n = 20), postmenopausal (n = 18) and men (n = 22).Demographic and clinical data are described in Table 1.Significant differences were found in age (p = 0.0001), weight (p = 0.0004), …

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Integrative metagenomic analysis reveals distinct gut microbial

WebObesity is a metabolic disorder closely associated with profound alterations in gut microbial composition. However, the dynamics of species composition and functional changes in the gut microbiome in obesity remain to be comprehensively investigated. In this study, we conducted a meta-analysis of metagenomic sequencing data from both obese …

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Effect of stress urinary incontinence on vaginal microbial …

WebBackground Postpartum women often experience stress urinary incontinence (SUI) and vaginal microbial dysbiosis, which seriously affect women’s physical and mental health. Understanding the relationship between SUI and vaginal microbiota composition may help to prevent vaginal diseases, but research on the potential association between …

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Interactions between host and gut microbiota in gestational …

WebGestational diabetes mellitus (GDM) is characterized by insulin resistance and low-grade inflammation, and most studies have demonstrated gut dysbiosis in GDM pregnancies. Overall, they were manifested as a reduction in microbiome diversity and richness, depleted short chain fatty acid (SCFA)-producing genera and a dominant of …

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