Biorxiv.org

Mapping single-cell developmental potential in health and

WebSingle-cell RNA sequencing (scRNA-seq) has transformed our understanding of cell fate in developmental systems. However, identifying the molecular …

Actived: 9 days ago

URL: https://www.biorxiv.org/content/10.1101/2024.03.19.585637v1

Longitudinal profiling of the microbiome at four body sites

WebTo understand dynamic interplay between the human microbiome and host during health and disease, we analyzed the microbial composition, temporal dynamics, …

Category:  Health Go Health

Psychobiological regulation of plasma and saliva GDF15

WebGDF15 (growth differentiation factor 15) is a marker of cellular energetic stress linked to physical-mental illness, aging, and mortality. However, questions remain about …

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Two Competing Guilds as a Core Microbiome Signature for

WebGut microbiota may work as an essential organ and its members interact closely with each other and form a higher-level organization called guilds. How such …

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Design of highly functional genome editors by modeling the

WebGene editing has the potential to solve fundamental challenges in agriculture, biotechnology, and human health. CRISPR-based gene editors derived from microbes, …

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Mapping single-cell developmental potential in health and

WebSingle-cell RNA sequencing (scRNA-seq) has transformed our understanding of cell fate in developmental systems. However, identifying the molecular …

Category:  Health Go Health

MetaCompare 2.0: Differential ranking of ecological and human …

WebBackground: While there is increasing recognition of numerous environmental contributions to the spread of antibiotic resistance, quantifying the relative …

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Medication Use is Associated with Distinct Microbial Features in

WebThis study investigated the relationship between gut microbiota and neuropsychiatric disorders (NPDs), specifically anxiety disorder (ANXD) and/or major …

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A regional One Health approach to the risk of invasion by

WebFor early detection of An. stephensi, the Vector Biology and Control Division under the Ministry of Health in Mauritius, leveraged a well-established Aedes program, …

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MDTraj: a modern, open library for the analysis of molecular

WebIn order to bridge this gap, we have developed MDTraj, a modern, open and lightweight Python library for analysis and manipulation of MD tra-jectories with the following goals: …

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The regulatory landscapes of human ovarian ageing bioRxiv

WebThe ovary is the first organ to age in the human body, affecting both fertility and overall health in women[1][1]-[8][2]. However, the biological mechanisms underlying …

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Phage as signatures of healthy microbiomes bioRxiv

WebWe set out to test whether viromes can be used as signatures of microbiome health using previously published results across systems. By comparing observed …

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ROBOCOV: An affordable open-source robotic platform for SARS …

WebCurrent global pandemic due to the SARS-CoV-2 has struggled and pushed the limits of global health systems. Supply chain disruptions and scarce availability of …

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National Database of Health Insurance Claims and Specific

WebMethods Our study targeted data from health insurance claims filed between April 2013 and March 2016 for hospitalization, combined diagnostic procedures, …

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Future Climate Scenarios Aggravate Health Risks of Soil

WebHow climate change affects the collection of antibiotic resistance genes (ARGs), called resistome, is a critical question for environmental and human health. By …

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Senotherapeutic peptide reduces skin biological age and

WebWe further validated the effectiveness of peptide 14 using human skin equivalents and skin biopsies, where peptide 14 promoted skin health and reduced …

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Noise Stress induces Cardiovascular Metabolic Shifts bioRxiv

WebEnvironmental stressors present in the modern world can fundamentally affect humans' physiology and health. Exposure to stressors like air pollution, heat, and …

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Antigenic cartography using hamster sera identifies SARS-CoV

WebAntigenic assessments of SARS-CoV-2 variants inform decisions to update COVID-19 vaccines. Primary infection sera are often used for assessments, but such …

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MetaCompare 2.0: Differential ranking of ecological and …

WebThe Meta-Compare 2.0 risk scores were remarkably consistent despite varying sequencing depth, contig count, and coverage. Conclusion: MetaCompare 2.0 …

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A torpor-like state (TLS) in mice slows blood epigenetic

WebProlonged induction of TLS slows epigenetic aging across multiple tissues and improves health span. We isolate the effects of decreased metabolic rate, long-term …

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Bioisosterism reveals new structure-odor relationships

WebThe allylic odorants, such. as tiglinaldehyde (TIG-4), 2-methyl 2-pentenal (TIG-5), and butyraldehyde (BUT), were. used to probe the relationship between cyclic and non-cyclic …

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