Healthy Volunteers Oncology Reviews
Listing Websites about Healthy Volunteers Oncology Reviews
Healthy volunteers in first-in-human oncology drug …
(1 days ago) WebThis review provides tools to consider the inclusion of healthy volunteers (HVs) in first-in-human (FIH) oncology clinical trials with small molecules, including …
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.15092
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Healthy Volunteer Studies in the Development of …
(Just Now) WebBackground Recent scientific advances in cancer research have led to the development of immunomodulatory and molecularly targeted drugs with better safety …
https://link.springer.com/article/10.1007/s43441-021-00330-8
Category: Cancer Show Health
Reviewing the role of healthy volunteer studies in drug
(1 days ago) WebBackground: With the exception of genotoxic oncology drugs, first-in-human, Phase 1 clinical studies of investigational drugs have traditionally been conducted in …
https://pubmed.ncbi.nlm.nih.gov/30509294/
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Frontiers Integration of healthy volunteers in early phase …
(4 days ago) WebA review of literature on published early phase clinical studies using immuno-oncology compounds in healthy volunteers following PRISMA guidelines and PROSPECT registration was …
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.954806/full
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Pivotal Considerations for Optimal Deployment of …
(1 days ago) WebOncology drug development is among the most challenging of any therapeutic area, with first-in-human trials expected to deliver information on both safety and activity. Until …
https://pubmed.ncbi.nlm.nih.gov/31674150/
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Use of healthy volunteers drives clinical oncology drug …
(2 days ago) WebPivotal Considerations for Optimal Deployment of Healthy Volunteers in Oncology Drug Development. Ahmed MA, Patel C, Drezner N, Helms W, Tan W, …
https://europepmc.org/article/MED/23010649
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Pivotal Considerations for Optimal Deployment of Healthy …
(3 days ago) WebREVIEW Pivotal Considerations for Optimal Deployment of Healthy Volunteers in Oncology Drug Development Mariam A. Ahmed1, Chirag Patel2, Nicole Drezner1, …
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12703
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Healthy Volunteer Studies in the Development of …
(4 days ago) WebAhmed MA, Patel C, Drezner N, Helms W, Tan W, Stypinski D. Pivotal considerations for optimal deployment of healthy Volunteers in Oncology Drug …
https://europepmc.org/article/PMC/PMC8688384
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Use of Healthy Volunteers Drives Clinical Oncology …
(3 days ago) WebThe development of noncytotoxic oncology therapeutics has opened the opportunity for clinical investigation beyond cancer patients. Utilization of the healthy-volunteer population has provided valuable …
https://ascpt.onlinelibrary.wiley.com/doi/10.1038/clpt.2012.157
Category: Cancer Show Health
Healthy Volunteers in First in Human Oncology Drug Development …
(3 days ago) WebThis review provides tools to consider the inclusion of healthy volunteers (HVs) in first in human (FIH) oncology clinical trials with small molecules, including …
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Reviewing the role of healthy volunteer studies in drug …
(7 days ago) WebBackground: With the exception of genotoxic oncology drugs, first-in-human, Phase 1 clinical studies of investigational drugs have traditionally been conducted in healthy …
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Healthy volunteers' perceptions of risk in US Phase I clinical - PLOS
(8 days ago) WebHealthy volunteers, after Johnson RA, Rid A, Emanuel E, Wendler D. Risks of phase I research with healthy participants: a systematic review. Clin Trials. …
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002698
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Healthy Volunteer Studies in the Development of Anticancer …
(3 days ago) WebRecent scientific advances in cancer research have led to the development of immunomodulatory and molecularly targeted drugs with better safety profiles than …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688384/
Category: Cancer Show Health
Integration of healthy volunteers in early phase clinical trials with
(3 days ago) WebA review of literature on published early phase clinical studies using immuno-oncology compounds in healthy volunteers following PRISMA guidelines and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465458/
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A Population Pharmacokinetic Meta-analysis of Sunitinib Malate …
(8 days ago) WebEach study protocol was reviewed and approved by Institutional Review Board, and informed consent was obtained from each subject. It included sunitinib and …
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Efficacy and safety of abemaciclib in combination with endocrine
(Just Now) Webe13096 Background: Breast cancer, particularly the HR+/HER2- subtype, remains a major global health concern. Abemaciclib, a CDK4/6 inhibitor, has shown …
https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.e13096
Category: Cancer Show Health
Comprehensive Hematology and Oncology Review Course marks …
(5 days ago) WebEach year, Fred Hutch's Comprehensive Hematology & Oncology Review Course attracts 100+ people in-person and many more online to learn about the latest …
Category: Course Show Health
Healthy volunteers in first‐in‐human oncology drug development …
(4 days ago) WebThis review provides tools to consider the inclusion of healthy volunteers (HVs) in first‐in‐human (FIH) oncology clinical trials with small molecules, including …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234445/
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Pivotal Considerations for Optimal Deployment of Healthy …
(3 days ago) WebOpportunities for healthy volunteer clinical pharmacology studies in oncology drug development: targeted agents, immunomodulatory agents, and beyond …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951451/
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Healthy volunteers in first‐in‐human oncology drug development …
(5 days ago) WebThis review provides tools to consider the inclusion of healthy volunteers (HVs) in first-in-human (FIH) oncology clinical trials with small molecules, including …
https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.15092
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Health equity in multi-cancer early detection (MCEDs): A literature
(9 days ago) Web10549 Background: Multi-cancer early detection tests (MCEDs) are an emerging screening technology to identify biomarkers of up to 50 different types of …
https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.10549
Category: Cancer Show Health
Mapping the mental health correlates of head and neck cancer: A
(8 days ago) Web6077 Background: Patients with head and neck cancer (HNC) present particularly high levels of mental health disorders. Yet the actual rate of relevant mental …
https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.6077
Category: Cancer Show Health
Healthy volunteers in first‐in‐human oncology drug …
(5 days ago) WebWhat is already known about this subject. • Inclusion of healthy volunteers has rarely been consid- ered for first-in-human (FIH) trials evaluating oncology therapeutics. • Generally, …
https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bcp.15092?download=true
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Reviewing the role of healthy volunteer studies in drug development
(3 days ago) WebWith the exception of genotoxic oncology drugs, first-in-human, Phase 1 clinical studies of investigational drugs have traditionally been conducted in healthy …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278009/
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Should I see an oncology genetic counselor? St Josephs / Candler
(1 days ago) WebYour oncologist or primary care physician can refer you or you can self-refer by calling the office at 912-819-8679. Genetic counselors do not meet with every single …
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Comprehensive molecular pathology review service to reduce …
(9 days ago) Web11129 Background: ECU Health system serves a rural 29-county region where cancer mortality rates exceed those of the state’s remaining 71 counties combined. …
https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.11129
Category: Cancer Show Health
Data driven evaluation of healthy volunteer characteristics at
(3 days ago) WebA systematic review and pooled analysis of select safety parameters among normal healthy volunteers taking placebo in phase 1 clinical trials. J Clin Pharmacol . …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604224/
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State and local efforts aim to ease access to heart care in rural
(5 days ago) WebIn a state where mountains and winding roads can make getting emergency services and health care hard, Kentuckians turn to technology and new training for help. …
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